Isisombululo se-Iron Dextran 20% Umxholo oPhezulu weDextran

Inkcazelo emfutshane:

Isisombululo se-Iron Dextran sisongezelelo sentsimbi esitofwayo esisetyenziselwa ukunyanga i-anemia yokusilela kwesinyithi kwizilwanyana.Sisinyibiliko esingenambala ukuya kumdaka-mnyama oqulathe iferric hydroxide kwicomplex ene dextran.Imveliso yenzelwe ukulawulwa kwe-intramuscular okanye ecothayo kwi-intravenous kwaye ifumaneka kwiindidi ezahlukeneyo kunye nomthamo ukuhlangabezana neemfuno zeentlobo ezahlukeneyo zezilwanyana kunye nobukhulu.Ngokufumaneka kwayo okuphezulu kwe-bioavailability kunye neprofayili yokhuseleko, i-Iron Dextran Solution lukhetho oluthembekileyo logqirha bezilwanyana abafuna ukuphucula impilo kunye nempilo yezigulane zabo.

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Iinkcukacha zeMveliso

Iithegi zeMveliso

Inkcazo

Igama:	Isisombululo se-Iron Dextran 20%
Elinye igama:	Iron dextran complex, ferric dextranum, ferric dextran, iron complex
INOMBOLO YECAS	9004-66-4
Umgangatho woMgangatho	I. CVP II.USP
Ifomula yemolekyuli	(C6H10O5)n·[Fe(OH)3]m
Inkcazo	Isisombululo secrystalloid esimdaka esimdaka ngebala, phenol kwincasa.
Isiphumo	Iyeza le-anti-anemia, elinokuthi lisetyenziswe kwi-anemia ye-iron-deficiency ye-piggies esanda kuzalwa kunye nezinye izilwanyana.
Uphawu	Ngomxholo ophezulu we-ferric xa kuthelekiswa neemveliso ezifanayo kwihlabathi.Inokufunxwa ngokukhawuleza kwaye ngokukhuselekileyo, isiphumo esihle.
Isivavanyi	I-200mgFe / ml kwifom yesisombululo.
Ukuphatha kunye noGcino	Ukugcina umgangatho ozinzileyo wemveliso, yigcine ngeqondo lokushisa;gcina kude nelanga kunye nokukhanya.
Iphakheji	Imigqomo yeplastiki ye-30L, i-50L, i-200L

Uhlalutyo kunye neNgxoxo

1. Ngokutofa i-1 ml ye-Futieli kumantshontsho eehagu aneminyaka engama-3 ubudala, afumana ubunzima obungama-21.10% kwiminyaka engama-60 ubudala.Le teknoloji kulula ukuyisebenzisa, ukulawula, kunye nokubonelela ngedosi echanekileyo, ekhokelela ekuzuzeni ubunzima kunye neenzuzo ezilungileyo.

2. Kwiintsuku ezingama-20, kwakungekho mmahluko obalulekileyo kubunzima obuqhelekileyo kunye nomxholo we-hemoglobin weehagu ezineminyaka eyi-3 ukuya kwe-19 iintsuku ezingazange zifumane i-iron supplementation.Nangona kunjalo, iqela lokulinga libonise umahluko omkhulu kubunzima bomzimba kunye nomxholo we-hemoglobin xa kuthelekiswa neqela lokulawula, elibonisa ukuba i-Futieli inokuphucula ubudlelwane bokubuyisela phakathi kobunzima kunye neempawu ze-hemoglobin kwiihagu.

3. Kwiintsuku zokuqala ezili-10 zokuzalwa, amantshontsho eehagu kumaqela okulinga kunye nokulawula ayengenamahluko omkhulu kubunzima bomzimba.Nangona kunjalo, bekukho ukungafani okuphawulekayo kumxholo we-hemoglobin, kunye ne-Futieli ebonisa ukukwazi ukuzinzisa amanqanaba e-hemoglobin yehagu phakathi kweentsuku ezili-10 emva kokutofa.Oku kuzinziswa kunika isiseko esiluqilima sokufumana ubunzima bexesha elizayo kunye nophuhliso.

iintsuku	iqela	ubunzima	ezuziweyo	thelekisa	ixabiso lamanani	thelekisa(g/100ml)
usana olusanda kuzalwa	yokulinga	1.26
	isalathiso	1.25
3	yokulinga	1.58	0.23	-0.01(-4.17)	8.11	+0.04
	isalathiso	1.50	0.24		8.07
10	yokulinga	2.74	1.49	+0.16(12.12)	8.76	+2,28
	isalathiso	2.58	1.32		6.48
20	yokulinga	4.85	3.59	+0.59(19.70)	10.47	+2,53
	isalathiso	4.25	3.00		7.94
60	yokulinga	15.77	14.51	+2.53(21.10)	12.79	+1,74
	isalathiso	13.23	11.98		11.98